反应详情

温度

60 °C

Diethylamine (2.66 g, 36.4 mMol) and 40 mL of ethanol were charged to a 100 mL RB flask equipped with a magnetic stirrer. The mixture was stirred and heated to 60° C. 2-{3-[Dimethyl-(2-trimethylsilanyl-ethyl)-silanyl]-propoxymethyl}-oxirane 8 (2 g; 7.28 mMol) mixed with 10 g ethanol was placed in an addition funnel and added dropwise to the flask. The mixture was stirred and maintained at 60° C. for an additional 8 hours. Ethanol and diethyl amine were stripped off on the rotovap. The mixture was distilled under vacuum to remove impurities.

1. customequipped with a magnetic stirrer
2. customwas placed in an addition funnel
3. additionadded dropwise to the flask
4. stirringThe mixture was stirred
5. temperaturemaintained at 60° C. for an additional 8 hours
6. distillationThe mixture was distilled under vacuum
7. customto remove impurities