HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1361293Generated: October 30, 2026
Oxalyl chloride → 2,2-Dimethyl-3-acetyloxypropionyl chloride
https://huagongshe.com/reaction/1361293
Participants
| Role | Name | HCID | Charge |
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| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 3-(Acetyloxy)-2,2-dimethylpropanoic acid | HCID 13192621 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 2,2-Dimethyl-3-acetyloxypropionyl chloride | HCID 11194663 | — |
Reaction Steps
The product of Step A, 2,2-dimethyl-3-acetyloxypropionic acid (11.76 g, 80 mmol) was dissolved in benzene (100 mL), the reaction solution was cooled 0° C., oxalyl chloride (15.0 g, 120 mmol) was slowly added dropwise. After 3 h, the solvent was removed in vacuo, and distilled in vacuo to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07879852B2 |
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| Source dataset | uspto-grants-2011_02 |
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| ORD ID | ord-4b5c65602ce6420b89b9f21bf9c0db30 |
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| Source note | uspto-grants-2011_02 |
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