Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1361537Generated: October 30, 2026

Ethyl 2-(2-aminothiazol-5-ylthio)acetate → {2-[3-(4-Fluoro-phenoxy)-5-((S)-2-methoxy-1-methyl-ethoxy)-benzoylamino]-thiazol-5-ylsulfanyl}-acetic Acid Ethyl Ester

https://huagongshe.com/reaction/1361537

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(2-aminothiazol-5-ylthio)acetateHCID 21455623—
Reactant3-(4-fluoro-phenoxy)-5-((S)-2-methoxy-1-methyl-ethoxy)-benzoic acidHCID 66969372—
Product{2-[3-(4-Fluoro-phenoxy)-5-((S)-2-methoxy-1-methyl-ethoxy)-benzoylamino]-thiazol-5-ylsulfanyl}-acetic Acid Ethyl EsterHCID 57776311—

Reaction Steps

The title compound was prepared from 3-(4-fluoro-phenoxy)-5-((S)-2-methoxy-1-methyl-ethoxy)-benzoic acid and (2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester following general procedure A

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07880012B2
Source datasetuspto-grants-2011_02
ORD IDord-ab6e067b5a4e4192ae6ce9a7bf477f70
Source noteuspto-grants-2011_02