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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1361555Generated: October 30, 2026

3-(4-fluoro-phenoxy)-5-((S)-2-methoxy-1-methyl-ethoxy)-benzoic acid → 3-{2-[3-(4-Fluoro-phenoxy)-5-((S)-2-methoxy-1-methyl-ethoxy)-benzoylamino]-thiazol-4-ylmethylsulfanyl}-propionic acid ethyl ester

https://huagongshe.com/reaction/1361555

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-fluoro-phenoxy)-5-((S)-2-methoxy-1-methyl-ethoxy)-benzoic acidHCID 66969372—
ReactantEthyl 3-{[(2-amino-1,3-thiazol-4-YL)methyl]sulfanyl}propanoateHCID 71414389—
Product3-{2-[3-(4-Fluoro-phenoxy)-5-((S)-2-methoxy-1-methyl-ethoxy)-benzoylamino]-thiazol-4-ylmethylsulfanyl}-propionic acid ethyl esterHCID 86632388—

Reaction Steps

3-{2-[3-(4-Fluoro-phenoxy)-5-((S)-2-methoxy-1-methyl-ethoxy)-benzoylamino]-thiazol-4-ylmethylsulfanyl}-propionic acid ethyl ester was prepared from 3-(4-fluoro-phenoxy)-5-((S)-2-methoxy-1-methyl-ethoxy)-benzoic acid and 3-(2-amino-thiazol-4-ylmethylsulfanyl)-propionic acid ethyl ester following general procedure A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07880012B2
Source datasetuspto-grants-2011_02
ORD IDord-c24c92397ef14a94b50ff5b242aaf35f
Source noteuspto-grants-2011_02