Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | HCID 23144385 | HCID 23144385 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 23144356 | HCID 23144356 | 40,585.801% |
Reaction Steps
Compound 502 (100 mg, 0.239 mmol) was suspended in 1,4-dioxane (1 mL), and morpholine (0.063 mL, 0.72 mmol) was added thereto, followed by stirring overnight at 100° C. The reaction mixture was concentrated under reduced pressure, and the resulting residue was reslurried with ethanol to afford the entitled Compound 503 (109 mg, 97 mmol) as a pale brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07880013B2 |
|---|
| Source dataset | uspto-grants-2011_02 |
|---|
| ORD ID | ord-ffb805a2094243ac822b8fa11e55f26d |
|---|
| Source note | uspto-grants-2011_02 |
|---|
