Methyl Ethyl Ketone → N-ethyl-N-(1-benzylpiperid-4-yl)-2-methoxy-4-trifluoroacetylamino-5-chlorobenzamide

HRID 136221Notes

Reaction equation

HRID 136221 reaction equation
[CH2:20]([c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)[N:27]1[CH2:28][CH2:29][CH:30]([NH:33][CH2:34][CH3:35])[CH2:31][CH2:32]1.[CH3:1][O:2][c:3]1[c:4]([C:5](=[O:6])[Cl:7])[cH:8][c:9]([Cl:19])[c:10]([NH:12][C:13]([C:14]([F:15])([F:16])[F:17])=[O:18])[cH:11]1.[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[CH3:43][C:44]([CH2:45][CH3:46])=[O:47]>>[CH3:1][O:2][c:3]1[c:4]([C:5](=[O:6])[N:33]([CH:30]2[CH2:29][CH2:28][N:27]([CH2:20][c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[CH2:32][CH2:31]2)[CH2:34][CH3:35])[cH:8][c:9]([Cl:19])[c:10]([NH:12][C:13]([C:14]([F:15])([F:16])[F:17])=[O:18])[cH:11]1

Participants

5

Reactant 4

HCID 6569Methyl Ethyl KetoneHCID 8471TriethylamineHCID 106088761-benzyl-N-ethylpiperidin-4-amineHCID 128664055-Chloro-2-methoxy-4-(2,2,2-trifluoroacetamido)benzoyl chloride

Product 1

HCID 12866406N-ethyl-N-(1-benzylpiperid-4-yl)-2-methoxy-4-trifluoroacetylamino-5-chlorobenzamide

Sources & evidence

ORD record
ord-6557e3aafdd041f38d83b9e05c958a1b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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