Dabco → HCID 58916981, compound

Participants

Reaction Steps

0.370 g 2-Amino-3-(4-ethoxy-phenoxy)-2methyl-1-morpholin-4-yl-propan-1-one and 0.276 g DABCO are dissolved in 8 ml tetrahydrofurane. After addition of 0.274 phenyl-methane sulfonyl chloride the mixture is stirred for 20 h at room temperature. This mixture is then subjected to flash chromatography without further work-up to yield 260 mg of a white solid. M.p. 109-111° C.

Provenance & Evidence