HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dabco → HCID 58916980, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dabco | HCID 9237 | — |
| Reactant | Phenylmethanesulfonyl chloride | HCID 74740 | — |
| Reactant | 2-Amino-3-(4-ethoxy-phenoxy)-2methyl-N-prop-2-ynyl-propionamide | HCID 86034476 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 58916980 | HCID 58916980 | — |
Reaction Steps
0.880 g 2-Amino-3-(4-ethoxy-phenoxy)-2methyl-N-prop-2-ynyl-propionamide and 0.233 g DABCO are dissolved in 8 ml tetrahydrofurane. After addition of 0.232 phenyl-methansulfonyl chloride the mixture is stirred for 20 hours. This mixture is then subjected to flash chromatography without further work-up to yield 320 mg of a white solid. M.p. 155-156° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07884103B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-10e5aaa86da2418490242689dbe2de66 |
| Source note | uspto-grants-2011_02 |