Phosphorus pentachloride → HCID 178506325, compound

HRID 1362899Notes

Reaction equation

HRID 1362899 reaction equation
[Cl:1][C:2]1[N:7]=[N:6][C:5]([NH:8][C:9](=O)[C:10]([F:13])([F:12])[F:11])=[CH:4][CH:3]=1.P(Cl)(Cl)(Cl)(Cl)[Cl:16]>ClC(Cl)C>[Cl:1][C:2]1[N:7]=[N:6][C:5](/[N:8]=[C:9](\[Cl:16])/[C:10]([F:13])([F:12])[F:11])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 86235795HCID 86235795, compound

Product 1

HCID 178506325HCID 178506325, compound

Reagents, catalysts & solvents 1

HCID 63651,1-DichloroethaneSolvent

Procedure

A solution of 3.8 g (17 mmol) of the crude product of Step A and 4.2 g (22 mmol) of phosphorous pentachloride in 200 mL of dichloroethane was heated at reflux temperature under nitrogen. After 6 h the reaction was cooled to ambient temperature then concentrated in vacuo to yield a crude oil which was carried on to Step C.

Workup

  1. temperatureat reflux temperature under nitrogen
  2. concentrationthen concentrated in vacuo
  3. customto yield a crude oil which

Sources & evidence

ORD record
ord-5e31c15ba87147b68d8838290b414a37
Source dataset
uspto-grants-2011_02
Patent number
US07884104B2

Reaction notes

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