Dichloromethane → HCID 57572396, compound

Participants

Reaction Steps

240 mg of tert-butyl 5-{3-[(5-chlorothiophene-2-carbonyl)amino]-1H-indazol-5-yl}furan-2-carboxylate are dissolved in 1 ml of trifluoroacetic acid and 3 ml of dichloromethane and stirred at room temperature for 24 hours. The batch is evaporated, the residue is stirred with dichloromethane, filtered off with suction and dried, giving 209 mg of 5-{3-[(5-chlorothiophene-2-carbonyl)amino]-1H-indazol-5-yl}furan-2-car-boxylic acid (“A20”) (quant.).

Provenance & Evidence