Benzaldehyde → N-(1-Benzyl-6-cyano-1,2,3,4-tetrahydroquinolin-3-yl)-benzenesulfonamide

HRID 1363119Notes

Reaction equation

HRID 1363119 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[NH:9][CH2:8][C@@H:7]([NH:13][S:14]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)(=[O:16])=[O:15])[CH2:6]2)#[N:2].[CH:23](=O)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH2:23]([N:9]1[C:10]2[C:5](=[CH:4][C:3]([C:1]#[N:2])=[CH:12][CH:11]=2)[CH2:6][CH:7]([NH:13][S:14]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)(=[O:16])=[O:15])[CH2:8]1)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 240BenzaldehydeHCID 66757946(S)-N-(6-Cyano-1,2,3,4-tetrahydro-quinolin-3-yl)-benzenesulfonamide

Product 1

HCID 66757116N-(1-Benzyl-6-cyano-1,2,3,4-tetrahydroquinolin-3-yl)-benzenesulfonamide

Procedure

Compound 165A was prepared from racemate 1G and benzaldehyde by procedures analogous to those described in Example 22A.

Sources & evidence

ORD record
ord-51133dc3aec14245aeb2e15f49ee0b2b
Source dataset
uspto-grants-2011_02
Patent number
US07884113B2

Reaction notes

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