Trifluoroacetic acid → HCID 66970592, compound

Participants

Reaction Steps

A solution of 1,3-dioxolane of (R)-tert-butyl 4-fluoro-2-(5-nitro-4-(4-oxo-1,2,3,4-tetrahydronaphthalen-1-ylamino)pyrimidin-2-ylamino)phenylcarbamate (145 mg) and TFA (2.5 mL) in CH2Cl2 (5 mL) was stirred at room temperature for 1 h. Volatiles were removed in vacuo and the crude (120 mg) was subjected to the next step without further purification.

Provenance & Evidence