Benzyl Bromide → Piperidinium, 1-methyl-4-oxo-1-(phenylmethyl)-, bromide

HRID 1363378Notes

Reaction equation

HRID 1363378 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][C:5](=[O:8])[CH2:4][CH2:3]1.[Br:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>CC(C)=O>[Br-:9].[CH2:10]([N+:2]1([CH3:1])[CH2:7][CH2:6][C:5](=[O:8])[CH2:4][CH2:3]1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

4

Reactant 2

HCID 7498Benzyl BromideHCID 740491-Methyl-4-piperidone

Product 1

HCID 10802960Piperidinium, 1-methyl-4-oxo-1-(phenylmethyl)-, bromide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution of 1-methyl-4-piperidinone (15 g, 132 mmol) in dry acetone (100 mL) was added 1-bromomethylbenzene (24.9 g, 145 mmol) dropwise. It was stirred for 3 h. The precipitated compound was filtered, washed with dry acetone and dried to get the title compound.

Workup

  1. filtrationThe precipitated compound was filtered
  2. washwashed with dry acetone
  3. customdried

Sources & evidence

ORD record
ord-4e881476333240e8a4b34c7eb5841662
Source dataset
uspto-grants-2011_02
Patent number
US07884127B2

Reaction notes

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