反应详情

To a solution of 1-methyl-4-piperidinone (15 g, 132 mmol) in dry acetone (100 mL) was added 1-bromomethylbenzene (24.9 g, 145 mmol) dropwise. It was stirred for 3 h. The precipitated compound was filtered, washed with dry acetone and dried to get the title compound.

1. filtrationThe precipitated compound was filtered
2. washwashed with dry acetone
3. customdried