Methyl 2-chloro-4-nitrobenzoate → Methyl 4-Amino-2-chlorobenzoate

HRID 1363412Notes

Reaction equation

HRID 1363412 reaction equation
[CH3:1][O:2][C:3](=[O:14])[C:4]1[CH:9]=[CH:8][C:7]([N+:10]([O-])=O)=[CH:6][C:5]=1[Cl:13]>[Fe]>[CH3:1][O:2][C:3](=[O:14])[C:4]1[CH:9]=[CH:8][C:7]([NH2:10])=[CH:6][C:5]=1[Cl:13]

Participants

3

Reactant 1

HCID 83343Methyl 2-chloro-4-nitrobenzoate

Product 1

HCID 11839197Methyl 4-Amino-2-chlorobenzoate

Reagents, catalysts & solvents 1

HCID 23925IronCatalyst

Procedure

Compound of example 161 (50 g, 232 mmol) was subjected to reduction using iron.

Sources & evidence

ORD record
ord-258efa2ecdaa42a898792c9c72ded009
Source dataset
uspto-grants-2011_02
Patent number
US07884127B2

Reaction notes

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