Potassium Cyanide → Methyl 2-chloro-5-cyanobenzoate

HRID 1363416Notes

Reaction equation

HRID 1363416 reaction equation
[CH3:1][O:2][C:3](=[O:12])[C:4]1[CH:9]=[C:8](N)[CH:7]=[CH:6][C:5]=1[Cl:11].[C:13]([Cu])#[N:14].[C-]#N.[K+]>>[CH3:1][O:2][C:3](=[O:12])[C:4]1[CH:9]=[C:8]([C:13]#[N:14])[CH:7]=[CH:6][C:5]=1[Cl:11]

Participants

4

Reactant 3

HCID 9032Potassium CyanideHCID 5200412Methyl 5-Amino-2-chlorobenzoateHCID 178418546HCID 178418546, compound

Product 1

HCID 16659388Methyl 2-chloro-5-cyanobenzoate

Procedure

5-Amino-2-chloro-benzoic acid methyl ester (10 g, 54 mmol) was diazotized followed by treatment with CuCN and KCN using the procedure described in example 165 to get the title compound.

Sources & evidence

ORD record
ord-542b3fd8d8994f4aac96296ef285f400
Source dataset
uspto-grants-2011_02
Patent number
US07884127B2

Reaction notes

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