Hydrochloric Acid → HCID 15979659, compound

Participants

Reaction Conditions

Reaction Steps

Tert.Butyl-4′-[4-Methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-n-propyl-1H-benzimidazol-1-yl-methyl]biphenyl-2-carboxylate hydrochloride (50 gms) is suspended in acetone (250 ml) and hydrochloric acid (50 ml) is added. Temperature of the mass is raised, maintained at 50° C.-55° C. for 3 hrs, cooled and maintained at 25-30° C. for 2 hrs. Product is filtered; wet cake is washed with water (2×50 ml) and acetone (50 ml). Dried the wet cake at temperature 60° C.-65° C. till constant weight.

Provenance & Evidence