4-Nitro-4'-(trifluoromethoxy)-1,1'-biphenyl → 4'-Trifluoromethoxy-biphenyl-4-ylamine

Participants

Reaction Steps

A mixture of 4-nitro-4′-(trifluoromethoxy)biphenyl (6.41 g, 22.6 mmol), 10% platinum-activated charcoal (150 mg) and methanol (50 ml) was stirred for 16 hours under hydrogen atmosphere. The reaction mixture was filtered through celite. The filtrate was concentrated under reduced pressure to give the title compound (5.48 g, 96%) as a white solid.

Provenance & Evidence