4-Methyl-1-indanone → 4-Methyl-2,3-dihydro-1H-inden-1-amine

HRID 1363669Notes

Reaction equation

HRID 1363669 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5][C:6]2=O.[BH3-]C#[N:14].[Na+]>>[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5][CH:6]2[NH2:14]

Participants

3

Reactant 2

HCID 44184314-Methyl-1-indanoneHCID 5003444Sodium cyanoborohydride

Product 1

HCID 227428304-Methyl-2,3-dihydro-1H-inden-1-amine

Procedure

The title amine was generated from 4-methyl-indan-1-one (5.00 g, 34.20 mmol), NaBH3CN (15.00 g, 0.24 mol) and NH4OAc (79.00 g, 1.02 mol) according to the protocols as outlined in general procedure B described above.

Sources & evidence

ORD record
ord-a5e7e3b722124ccf87fc1da9d68e1f57
Source dataset
uspto-grants-2011_02
Patent number
US07884244B2

Reaction notes

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