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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1363715Generated: October 30, 2026

Benzenepropanal → {2-[3-(4-Methyl-cyclohexyl)-3-(3-phenyl-propyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid

https://huagongshe.com/reaction/1363715

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenepropanalHCID 7707—
Reactant[2-(3-Cyclohexyl-3-phenethylureido)-thiazol-5-ylsulfanyl]-acetic acidHCID 11993791—
ReactantEthyl 2-(2-aminothiazol-5-ylthio)acetateHCID 21455623—
ReactantHCID 178461305HCID 178461305—
Product{2-[3-(4-Methyl-cyclohexyl)-3-(3-phenyl-propyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acidHCID 57668212—

Reaction Steps

Prepared as described for the synthesis of [2-(3-cyclohexyl-3-phenethyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid using 3-phenylpropionaldehyde, trans-4-methyl-cyclohexylamine and (2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07884210B2
Source datasetuspto-grants-2011_02
ORD IDord-3e2f4e34ae5c4de1b06fb9eac789f090
Source noteuspto-grants-2011_02