Isoamylamine → HCID 57668372, compound

HRID 1363727Notes

Reaction equation

HRID 1363727 reaction equation
[CH:1]1([N:7]([CH2:21][CH2:22][C:23]2[CH:28]=CC=C[CH:24]=2)[C:8](=[O:20])[NH:9][C:10]2[S:11][C:12]([S:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:13][N:14]=2)[CH2:6][CH2:5][CH2:4]CC1.[CH:29](=O)CC(C)C.CC(C)CCN.C(OC(=O)CSC1SC(N)=NC=1)C>>[CH3:29][CH:5]([CH3:4])[CH2:6][CH2:1][N:7]([CH2:21][CH2:22][CH:23]([CH3:24])[CH3:28])[C:8](=[O:20])[NH:9][C:10]1[S:11][C:12]([S:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:13][N:14]=1

Participants

5

Reactant 4

HCID 7894IsoamylamineHCID 115523-MethylbutanalHCID 11993791[2-(3-Cyclohexyl-3-phenethylureido)-thiazol-5-ylsulfanyl]-acetic acidHCID 21455623Ethyl 2-(2-aminothiazol-5-ylthio)acetate

Product 1

HCID 57668372HCID 57668372, compound

Procedure

Prepared as described for the synthesis of [2-(3-cyclohexyl-3-phenethyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid using isovaleraldehyde, 3-methylbutylamine and (2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-891c9c892c494d828f8263a5e8e611e0
Source dataset
uspto-grants-2011_02
Patent number
US07884210B2

Reaction notes

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