Isoamylamine → HCID 57668452, compound
Reaction equation
[CH:1]1([N:7]([CH2:21][CH2:22][C:23]2[CH:28]=CC=C[CH:24]=2)[C:8](=[O:20])[NH:9][C:10]2[S:11][C:12]([S:15][CH2:16][C:17](O)=O)=[CH:13][N:14]=2)[CH2:6][CH2:5][CH2:4]CC1.[CH:29](=O)CC(C)C.CC(C)CCN.C([O:43][C:44](=[O:54])C(SC1SC(N)=NC=1)C)C>>[CH3:29][CH:5]([CH3:4])[CH2:6][CH2:1][N:7]([CH2:21][CH2:22][CH:23]([CH3:24])[CH3:28])[C:8](=[O:20])[NH:9][C:10]1[S:11][C:12]([S:15][CH2:16][CH2:17][C:44]([OH:54])=[O:43])=[CH:13][N:14]=1Participants
5
Procedure
Prepared as described for the synthesis of [2-(3-cyclohexyl-3-phenethyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid using isovaleraldehyde, 3-methyl-butylamine and (2-amino-thiazol-5-ylsulfanyl)-propionic acid ethyl ester.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-fe22e716bdcc460d8f97fe94a9ebbcbc
- Source dataset
- uspto-grants-2011_02
- Patent number
- US07884210B2
Reaction notes
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