Isoamylamine → HCID 57668315, compound

HRID 1363731Notes

Reaction equation

HRID 1363731 reaction equation
[CH:1]1([N:7]([CH2:21][CH2:22][C:23]2[CH:28]=CC=C[CH:24]=2)[C:8](=[O:20])NC2SC(SCC(O)=O)=CN=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C1(=O)CCCCC1.CC(C)CCN.C([O:44][C:45](=[O:56])[C:46]([S:49][C:50]1[S:54][C:53]([NH2:55])=[N:52][CH:51]=1)([CH3:48])[CH3:47])C>>[CH:1]1([N:7]([CH2:21][CH2:22][CH:23]([CH3:28])[CH3:24])[C:8](=[O:20])[NH:55][C:53]2[S:54][C:50]([S:49][C:46]([CH3:47])([CH3:48])[C:45]([OH:44])=[O:56])=[CH:51][N:52]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

5

Reactant 4

HCID 7894IsoamylamineHCID 7967CyclohexanoneHCID 11993791[2-(3-Cyclohexyl-3-phenethylureido)-thiazol-5-ylsulfanyl]-acetic acidHCID 57481427Ethyl 2-[(2-amino-1,3-thiazol-5-yl)sulfanyl]-2-methylpropanoate

Product 1

HCID 57668315HCID 57668315, compound

Procedure

Prepared as described for the synthesis of [2-(3-cyclohexyl-3-phenethyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid, from cyclohexanone, 3-methylbutylamine and 2-(2-amino-thiazol-5-ylsulfanyl)-2-methyl-propionic acid ethyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e58e2021412949578001b46a95a9baf7
Source dataset
uspto-grants-2011_02
Patent number
US07884210B2

Reaction notes

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