Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1363819Generated: October 31, 2026

Ethyl 2-(2-aminothiazol-5-ylthio)acetate → HCID 57668374, compound

https://huagongshe.com/reaction/1363819

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(2-aminothiazol-5-ylthio)acetateHCID 21455623—
Reactant{2-[3-Cyclopentylmethyl-3-(4-methanesulfonyl-phenyl)-ureido]thiazol-4-yl}-acetic acidHCID 57668194—
Reactant4-Bromo-N-(cyclopentylmethyl)-2-fluoroanilineHCID 63419246—
ProductHCID 57668374HCID 57668374—

Reaction Steps

The title compound was prepared via {2-[3-(4-bromo-2-fluoro-phenyl)-3-cyclopentylmethyl-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl esterin a similar manner as described for the synthesis of {2-[3-cyclopentylmethyl-3-(4-methanesulfonyl-phenyl)-ureido]-thiazol-4-yl}-acetic acid, using cyclopentylmethyl-(4-bromo-2-fluoro-phenyl)-amine and (2-amino-thiazol-5-ylsulfanyl)acetic acid ethyl ester

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07884210B2
Source datasetuspto-grants-2011_02
ORD IDord-a030b6d63e1445528a128ff0548e9a1f
Source noteuspto-grants-2011_02