Succinic anhydride → HCID 12615272, compound
Reaction equation
[NH:1]1[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[C:7]1(=[O:13])[O:12][C:10](=[O:11])[CH2:9][CH2:8]1.C(OCC)(=[O:16])C>>[O:4]1[CH2:5][CH2:6][N:1]([CH:8]([CH2:9][C:10]([OH:16])=[O:11])[C:7]([OH:12])=[O:13])[CH2:2][CH2:3]1Participants
4
Procedure
Morpholine and succinic acid anhydride were dissolved in ethyl acetate and the solution was refluxed. The solvent was evaporated to obtain a crude product of morpholino succinic acid
Workup
- temperaturethe solution was refluxed
- customThe solvent was evaporated
Sources & evidence
- ORD record
- ord-c803fd4e850c4908b4d85df08a683c9f
- Source dataset
- uspto-grants-2011_02
- Patent number
- US07887835B2
Reaction notes
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