Bromine → 2-Bromo-4,4-dimethylcyclohexane-1,3-dione

HRID 1364086Notes

Reaction equation

HRID 1364086 reaction equation
[CH3:1][C:2]1([CH3:10])[CH2:7][CH2:6][C:5](=[O:8])[CH2:4][C:3]1=[O:9].[Br:11]Br>CC(O)=O>[Br:11][CH:4]1[C:3](=[O:9])[C:2]([CH3:10])([CH3:1])[CH2:7][CH2:6][C:5]1=[O:8]

Participants

4

Reactant 2

HCID 24408BromineHCID 1363601,3-Cyclohexanedione, 4,4-dimethyl-

Product 1

HCID 543872942-Bromo-4,4-dimethylcyclohexane-1,3-dione

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

To a stirred solution of 4,4-dimethylcyclohexane-1,3-dione (1.4 g, 10 mmol) in AcOH (20 mL) at r.t. was added bromine (1.6 g, 0.51 mL, 10 mmol) dropwise. The reaction was carried out according to Method A to give the title compound in quantitative yield as a light brown solid which was used without further purification. LCMS (ES+) 218.9 (+H)+.

Sources & evidence

ORD record
ord-b19c2c990f6946b3947aea68e390fd38
Source dataset
uspto-grants-2011_02
Patent number
US07888344B2

Reaction notes

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