HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 2-Bromo-4,4-dimethylcyclohexane-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1,3-Cyclohexanedione, 4,4-dimethyl- | HCID 136360 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-Bromo-4,4-dimethylcyclohexane-1,3-dione | HCID 54387294 | — |
Reaction Steps
To a stirred solution of 4,4-dimethylcyclohexane-1,3-dione (1.4 g, 10 mmol) in AcOH (20 mL) at r.t. was added bromine (1.6 g, 0.51 mL, 10 mmol) dropwise. The reaction was carried out according to Method A to give the title compound in quantitative yield as a light brown solid which was used without further purification. LCMS (ES+) 218.9 (+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07888344B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-b19c2c990f6946b3947aea68e390fd38 |
| Source note | uspto-grants-2011_02 |