2-Chlorobenzoic Acid → 2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)benzamide

HRID 1364640Notes

Reaction equation

HRID 1364640 reaction equation
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1.[Cl:15][C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18](O)=[O:19]>>[Cl:15][C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18]([NH:6][C:5]1[CH:7]=[CH:8][C:2]([Cl:1])=[C:3]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=2)[CH:4]=1)=[O:19]

Participants

3

Reactant 2

HCID 83742-Chlorobenzoic AcidHCID 401519254-Chloro-3-(pyridin-2-yl)aniline

Product 1

HCID 454857892-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)benzamide

Procedure

Procedure G was used to couple 4-chloro-3-(pyridin-2-yl)aniline (50 mg) and 2-chlorobenzoic acid to produce 2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)benzamide. MS (Q1) 343.1 (M)+.

Sources & evidence

ORD record
ord-2696f1d88a764f1786a03d53ad63328b
Source dataset
uspto-grants-2011_02
Patent number
US07888364B2

Reaction notes

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