huagongshe.com
HRID1364749

反应详情

EQUATION

反应方程式

HRID 1364749 的结构方程式

REACTANTS

反应物

2
结构：Nc1ccc(N)nc1
HCID20314

Pyridine, 2,5-diamino-

C5H7N3

结构：O=C(O)c1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)c(Cl)c1
HCID66878605

未命名化合物

PRODUCTS

生成物

1
结构：Nc1ccc(NC(=O)c2ccc(C(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)c(Cl)c2)cn1
HCID58614771

未命名化合物

PROCEDURE

实验过程

50 mg of 3-chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acid was coupled to pyridine-2,5-diamine via Procedure G. The crude product was purified on reverse phase HPLC to yield N4-(6-aminopyridin-3-yl)-2-chloro-N1-(4-chloro-3-(pyridin-2-yl)phenyl)terephthalamide. MS (Q1) 478 (M)+.

WORKUP

后处理

  1. customThe crude product was purified on reverse phase HPLC