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HRID1364822

反应详情

EQUATION

反应方程式

HRID 1364822 的结构方程式

REACTANTS

反应物

2
反应SMILES：O=C(O)c1ccc(-n2ccnc2)cc1
HCID736529

4-(1H-Imidazol-1-yl)benzoic acid

C10H8N2O2

反应SMILES：Nc1ccc(Cl)c(-c2ccccn2)c1
HCID40151925

4-Chloro-3-(pyridin-2-yl)aniline

C11H9ClN2

PRODUCTS

产物

1
反应SMILES：O=C(Nc1ccc(Cl)c(-c2ccccn2)c1)c1ccc(-n2ccnc2)cc1
HCID58614654

未命名化合物

PROCEDURE

实验过程

75 mg of 4-chloro-3-(pyridin-2-yl)aniline was coupled to 78 mg of 4-(1H-imidazol-1-yl)benzoic acid via Procedure G. The crude product was purified by reverse phase HPLC to yield N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(1H-imidazol-1-yl)benzamide. MS (Q1) 375.3 (M)+.

WORKUP

后处理

  1. customThe crude product was purified by reverse phase HPLC