Hydroxyamine hydrochloride → HCID 72346776, compound

Temperature

23 °C

To a solution of 5-(methylthio)furan-2-carbaldehyde (1.0 g, 7.04 mmol) in ethanol (10 mL) was added an aqueous solution of hydroxylamine hydrochloride (3.75M) (2.26 mL, 8.45 mmol) and an aqueous solution of sodium acetate (1.5 M) (3.78 mL, 5.63 mmol). The reaction mixture was stirred a 23° C. for 18 hours. The ethanol was concentrated in vacuo, H2O was added (50 mL) and the precipitate was filtered and dried in oven (60° C.) for 10 minutes to afford 277 mg (25%) of the title compound. LCMS (+ESI, M+H+) m/z 158.

1. concentrationThe ethanol was concentrated in vacuo, H2O
2. additionwas added (50 mL)
3. filtrationthe precipitate was filtered
4. customdried in oven (60° C.) for 10 minutes

ORD record

ord-8b8574e7a6094b56bb9615673cf4abdc

Source dataset

uspto-grants-2011_02

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US07893055B2