1,1-Dimethylethyl 2,2-dimethyl-1-piperazinecarboxylate → 4-(5-Chloro-7-morpholin-4-ylthiazolo[4,5-d]pyrimidin-2-ylmethyl)-2,2-dimethylpiperazine-1-carboxylic acid tert-butyl ester

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Reaction Steps

Prepared according to the method used in the preparation of 5-(5-chloro-7-morpholin-4-ylthiazolo[4, 5-d]-pyrimidin-2-ylmethyl)-hexahydro-pyrrolo[3,4-c]pyrrole-2-carboxylic acid tert-butyl ester using 2,2-dimethylpiperazine-1-carboxylic acid tert-butyl ester in place of hexahydro-pyrrolo[3,4-c]pyrrole-2-carboxylic acid tert-butyl ester. The title compound was obtained as a yellow solid (100 mg, 38%).

Provenance & Evidence