1-Cyclopropylpiperazine → HCID 58234951, compound

HRID 1365877Notes

Reaction equation

HRID 1365877 reaction equation
N1(C2C[CH2:9][N:8]([CH2:11][C:12]3[S:13][C:14]4[N:15]=[C:16]([Cl:27])[N:17]=[C:18]([N:21]5[CH2:26][CH2:25][O:24][CH2:23][CH2:22]5)[C:19]=4[N:20]=3)CC2)CCC1.[CH:28]1([N:31]2[CH2:36]CN[CH2:33][CH2:32]2)[CH2:30][CH2:29]1>>[Cl:27][C:16]1[N:17]=[C:18]([N:21]2[CH2:26][CH2:25][O:24][CH2:23][CH2:22]2)[C:19]2[N:20]=[C:12]([CH2:11][N:8]3[CH2:33][CH2:32][N:31]([CH:28]4[CH2:30][CH2:29]4)[CH2:36][CH2:9]3)[S:13][C:14]=2[N:15]=1

Participants

3

Reactant 2

HCID 47420041-CyclopropylpiperazineHCID 582349332-(4-Azetidin-1-ylpiperidin-1-ylmethyl)-5-chloro-7-morpholin-4-ylthiazolo[5,4-d]pyrimidine

Product 1

HCID 58234951HCID 58234951, compound

Procedure

Prepared according to the method used in the preparation of 2-(4-azetidin-1-ylpiperidin-1-ylmethyl)-5-chloro-7-morpholin-4-ylthiazolo[5,4-d]pyrimidine using 1-cyclopropylpiperazine in place of 4-azetidin-1-ylpiperidine. The title compound was obtained as a white solid (117 mg, 56%).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-489d5af4c3b6458dba214de919863534
Source dataset
uspto-grants-2011_02
Patent number
US07893060B2

Reaction notes

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