Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1365878Generated: October 26, 2026

N,N-Dimethylpiperidin-4-amine → [1-(5-Chloro-7-morpholin-4-ylthiazolo[5,4-d]pyrimidin-2-ylmethyl)piperidin-4-yl]dimethylamine

https://huagongshe.com/reaction/1365878

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-Dimethylpiperidin-4-amineHCID 417391—
Reactant2-(4-Azetidin-1-ylpiperidin-1-ylmethyl)-5-chloro-7-morpholin-4-ylthiazolo[5,4-d]pyrimidineHCID 58234933—
Product[1-(5-Chloro-7-morpholin-4-ylthiazolo[5,4-d]pyrimidin-2-ylmethyl)piperidin-4-yl]dimethylamineHCID 58234944—

Reaction Steps

Prepared according to the method used in the preparation of 2-(4-azetidin-1-ylpiperidin-1-ylmethyl)-5-chloro-7-morpholin-4-ylthiazolo[5,4-d]pyrimidine using dimethylpiperidin-4-ylamine in place of 4-azetidin-1-ylpiperidine. The title compound was obtained as a pale yellow solid (101 mg, 72%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07893060B2
Source datasetuspto-grants-2011_02
ORD IDord-a5156f47902145519cab7982c40b831b
Source noteuspto-grants-2011_02