HRID1365895

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CS(=O)(=O)O.NCCC[C@H](N)C(=O)N[C@H](CCc1ccccc1)C(=O)Nc1cnc2ccccc2c1

HCID11663539

未命名化合物

结构：CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)[C@@H](CCCN)C(=O)N[C@H](Cc1cc(F)c(F)c(F)c1)C(=O)O.NC(=O)c1cnc2ccccc2c1

HCID86602424

未命名化合物

PRODUCTS

生成物

结构：CS(=O)(=O)O.NC(=O)c1cnc2ccccc2c1.NCCC[C@H](N)C(=O)N[C@H](Cc1cc(F)c(F)c(F)c1)C(=O)O

HCID86602422

未命名化合物

PROCEDURE

实验过程

NaNd-bis-Boc-L-ornithyl-(3,4,5-trifluoro)-D-Phenylalanine Quinoline-3-amide was converted into mono-mesylate salt of the tile product according to the procedure described for compound 3 to give the title product (0.15 g) as off white solid.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-90f72fe61c33407ca33111411e4b7e16
来源数据集: uspto-grants-2011_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07893020B2
来源说明: uspto-grants-2011_02

反应 SMILES

[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]([C:11]([NH2:13])=[O:12])[CH:2]=1.C([N:21](C(OC(C)(C)C)=O)[C@H:22]([C:27]([NH:29][C@@H:30]([C:41]([OH:43])=[O:42])[CH2:31][C:32]1[CH:37]=[C:36]([F:38])[C:35]([F:39])=[C:34]([F:40])[CH:33]=1)=[O:28])[CH2:23][CH2:24][CH2:25][NH2:26])(OC(C)(C)C)=O.[CH3:51][S:52]([OH:55])(=[O:54])=[O:53].C1(CC[C@@H](NC(=O)[C@@H](N)CCCN)C(=O)NC2C=NC3C(C=2)=CC=CC=3)C=CC=CC=1>>[S:52]([OH:55])(=[O:54])(=[O:53])[CH3:51].[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]([C:11]([NH2:13])=[O:12])[CH:2]=1.[NH2:21][C@H:22]([C:27]([NH:29][C@@H:30]([C:41]([OH:43])=[O:42])[CH2:31][C:32]1[CH:33]=[C:34]([F:40])[C:35]([F:39])=[C:36]([F:38])[CH:37]=1)=[O:28])[CH2:23][CH2:24][CH2:25][NH2:26]