HCID 59411295, compound → HCID 59411327, compound

Participants

Reaction Steps

tert-Butyl 3-{[6-(4-cyanophenyl)-5-(2-furoyl)-4-methyl-2-oxo-3-[3-(trifluoromethyl)phenyl]-3,6-dihydropyrimidin-1(2H)-yl]methyl}benzoate (Example 43) (50 mg, 0.078 mmol) is dissolved in trifluoroacetic acid (2 ml). After 15 minutes stirring, the solution is concentrated in vacuo and the residue is purified by preparative HPLC (RP18 column; eluent: acetonitrile/water 10:90→90:10).

Provenance & Evidence