Hydrochloric Acid → HCID 66935862, compound

Participants

Reaction Steps

N,N-Dimethyl-2-[1-(phenylmethyl)-3-pyrrolidinyl]-2-propanamine (2.089 g, 8.47 mmol) was dissolved in a mixture of MeOH (50 mL) and 1N HCl (18.65 mL, 18.65 mmol), degassed and placed under argon. 10% Pd/C (625 mg) was added, and the contents were thoroughly degassed and placed under a hydrogen balloon for 2 h. The contents were then degassed, and the Pd/C was removed by filtration through a fiberglass filter, washing with MeOH. The filtrate was concentrated in vacuo to provide pure N,N-dimethyl-2-(3-pyrrolidinyl)-2-propanamine hydrochloride (1.245 g, 76%). LCMS: (M+H)+: 157.2.

Provenance & Evidence