2-Chloro-4-(trifluoromethyl)benzenesulfonyl chloride → 2-Chloro-N-{4-methyl-6-[4-(piperidine-1-sulfonyl)-phenylsulfanyl]-pyridazin-3-yl}-4-trifluoromethyl-benzenesulfonamide

Participants

Reaction Steps

Can be prepared from 4-methyl-6-[4-(piperidine-1-sulfonyl) -phenylsulfanyl]-pyridazin-3-ylamine and 2-chloro-4-trifluoromethylbenzenesulfonyl chloride. 1H NMR (CDCl3) 8.30 (1H, d) 7.75 (2H, m) 7.70(1H, s) 7.6(3H, m) 7.05(1H, s) 3.0 (4H, m) 2.1 (3H, s) 1.6(4H, m) 1.40(2H, m) LCMS Polarity/Scan type: Negative Q1 Scan. M.wt. 605 (—H), 607 (—H). Retention time 7.39 minutes. HPLC MS8 Retention time 5.36 minutes.

Provenance & Evidence