2-Oxa-6-azaspiro[3.3]heptane → HCID 49835732, compound

Participants

Reaction Steps

The title compound was prepared by reaction of (1R,2R,4R)-4-benzenesulfonyl-2-(1-cyano-cyclopropylcarbamoyl)-cyclopentanecarboxylic acid (example 10) with 2-oxa-6-aza-spiro[3.3]heptane (prepared according to G. Wuitschik et al., Angew. Chem., Int. Ed., 47, 4512, 2008) using a procedure as described in example 1, step 8. Colorless foam. MS: 444.3 (M+H)+.

Provenance & Evidence