Hydrogen Bromide → 2-amino-7-(p-chlorophenylacetyl)-6,7,8,9-tetrahydro-5H-pyrazino[2,3-d]azepine
Reaction equation
[BrH:1].[BrH:2].[Cl:15][c:16]1[cH:17][cH:18][c:19]([CH2:22][C:23](=[O:24])[Cl:25])[cH:20][cH:21]1.[NH2:3][c:4]1[cH:5][n:6][c:7]2[c:8]([n:14]1)[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2.[Na+:27].[O:28]1[CH2:29][CH2:30][O:31][CH2:32][CH2:33]1.[OH-:26]>>[NH2:3][c:4]1[cH:5][n:6][c:7]2[c:8]([n:14]1)[CH2:9][CH2:10][N:11]([C:23]([CH2:22][c:19]1[cH:18][cH:17][c:16]([Cl:15])[cH:21][cH:20]1)=[O:24])[CH2:12][CH2:13]2Participants
7
Sources & evidence
- ORD record
- ord-ebb772f6114a4cf8921c2a3decf7b901
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…