Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1367594Generated: October 29, 2026

1-Isopropylpiperazine → HCID 59619366, compound

https://huagongshe.com/reaction/1367594

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-IsopropylpiperazineHCID 78013—
ReactantHCID 59619432HCID 59619432—
Reactant(1S,2S,4S)-4-(4-Bromo-2-trifluoromethyl-benzenesulfonyl)-2-methoxy-cyclopentanecarboxylic acid (1-cyano-cyclopropyl)-amideHCID 59619475—
ProductHCID 59619366HCID 59619366—

Reaction Steps

The title compound was prepared in analogy to example 176 using 1-isopropyl-piperazine instead of morpholine and (1R,2R,4R) and (1S,2S,4S)-4-(4-bromo-2-trifluoromethyl-benzenesulfonyl)-2-cyclopentyloxy-cyclopentanecarboxylic acid (1-cyano-cyclopropyl)-amide (example 195) instead of (1R,2R,4R) and (1S,2S,4S)-4-(4-bromo-2-trifluoromethyl-benzenesulfonyl)-2-methoxy-cyclopentanecarboxylic acid (1-cyano-cyclopropyl)-amide. White solid. MS (EI): 595.4 (M−H)−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07893099B2
Source datasetuspto-grants-2011_02
ORD IDord-2f11b46839a24bfca15866afc0cfcd48
Source noteuspto-grants-2011_02