HCID 11561933, compound → HCID 11635901, compound

Participants

Reaction Steps

(4S,5R)-4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 7) was reacted with 1-(2-methanesulfonylethyl)-piperazine bishydrochloride in methylene chloride using the procedure as described in example 8 to give [(4S,5R)-4,5-bis-(4-chloro-phenyl)-2-(2-ethoxy-phenyl)-4,5-dihydro-imidazol-1-yl]-[4-(2-methanesulfonyl-ethyl)-piperazin-1-yl]-methanone. HR-MS (ES, m/z) calculated for C31H35N4O4SCl2 [(M+H)+] 629.1751, observed 629.1757.

Provenance & Evidence