Acetic Acid → HCID 86613018, compound

Participants

Reaction Steps

30 gms of sertraline base is dissolved in 200 ml of toluene under stirring at room temp. 5 ml acetic acid is added to the clear toluene solution and stirred for 1 hr. at 25° C. to obtain a thick white precipitate. The solids are filtered and re-slurried in 100 ml toluene for 30 minutes and filtered. The product is dried under vacuum at 60° C. for 5-6 hours to give sertraline acetate.

Provenance & Evidence