HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 18520196, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 57208345 | HCID 57208345 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 18520196 | HCID 18520196 | 72.7% |
Reaction Steps
230 mg of 2-[4-(4-chloro-5-formyl-2-phenylimidazol-1-ylmethyl)benzenesulfonyl]-N-dimethylaminomethylenebenzenesulfonamide are refluxed for 2 h in 3 ml of EtOH and 3 ml of a saturated aqueous HCl solution. The reaction mixture is allowed to cool and poured onto 10 ml of water, and the product is filtered off. Chromatography on silica gel using MTB yields 151 mg of an amorphous solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06573288B1 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-3c250b97b83a4d398c0c4c72c6eb4cf9 |
| Source note | uspto-grants-2003_06 |