Phosphorus oxychloride → 7-(1-acetyl-1-methyl-4-phenylbutyl)-2-(3,4-dimethoxy-benzyl)-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one

Participants

Reaction Steps

Analogously to Example 1, 3.08 g (6.07 mmol) of 2-acetyl-N-{1-[3-(3,4-dimethoxybenzyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]ethyl}-2-methyl-5-phenylpentanamide and 4.44 mg (29.0 mmol) of phosphorus oxychloride are reacted to give 7-(1-acetyl-1-methyl-4-phenylbutyl)-2-(3,4-dimethoxybenzyl)-5-methylimidazo[5,1-f][1,2,4]-triazin-4(3H)-one.

Provenance & Evidence