1-Methylpiperazine → 2-(2-Hydroxyphenyl)-1-(4-methylpiperazino)-1-ethanone
반응식
[CH3:1][N:2]1[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1.[O:8]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH2:10][C:9]1=[O:17]>>[OH:8][C:16]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[CH2:10][C:9]([N:5]1[CH2:6][CH2:7][N:2]([CH3:1])[CH2:3][CH2:4]1)=[O:17]참가 물질
3
반응 조건
- 온도
- 85 °C
실험 절차
N-Methylpiperazine (1.52 g) was added to 2-coumaranone (2.01 g) and stirred for 3.5 hours at 85° C., thereby yielding the entitled compound (3.57 g) as pale brown solid.
출처 및 근거
- ORD 기록
- ord-35a45de58a02443fbf35d49473533310
- 출처 데이터셋
- uspto-grants-2003_06
- 특허 번호
- US06573297B2
반응 노트
불러오는 중…