反应详情

温度

80 °C

3.0 g (19 mmol) of ethyl 2-allyloxypropionate are introduced into 4.5 g (28.5 mmol) of 9-decen-1-ol, and 0.56 g (2 mmol) of Ti(OiPr)4 are added. The mixture is then heated to 80° C. and stirred at a reduced pressure of 400 mbar for 5 h. A few drops of water are then added and the crude product is purified by means of flash chromatography (cyclohexane/EtOAc=25:1; Rf=0.21), giving 4.1 g (81%) of a colorless oil.

1. additionare added
2. customthe crude product is purified by means of flash chromatography (cyclohexane/EtOAc=25:1; Rf=0.21)