HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon Dioxide → 4-Chloro-2-methylbenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon Dioxide | HCID 280 | — |
| Reactant | 2-Bromo-5-chlorotoluene | HCID 84476 | — |
| Reactant | N-(2-Methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine | HCID 9799487 | — |
| Product | 4-Chloro-2-methylbenzoic acid | HCID 348269 | — |
Reaction Steps
In a process for preparing N-diaminomethylene-2-methyl-4,5-di(methylsulfonyl)benzamide, the step comprising reacting 2-bromo-5-chlorotoluene with a secondary or tertiary organolithium compound and CO2 to produce 4-chloro-2-methylbenzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06573404B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-8be301c50dbe41088f92d51e48345868 |
| Source note | uspto-grants-2003_06 |