HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 86759005, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Ethyl formate | HCID 8025 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 22169004 | HCID 22169004 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 86759005 | HCID 86759005 | — |
Reaction Steps
A mixture of 24 g biphenylacetic acid ethyl ester and 8.2 g ethyl formate is added dropwise while stirring to a suspension of 2.4 g sodium hydride in 250 ml ether. The reaction mixture is stirred for 2 hours at room temperature and cold water is carefully added. The aqueous phase is acidified to pH 2 and the product is extracted with ether. The extract is dried and concentrated by evaporation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06576628B1 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-867325a18a984dc38b444e5b66dda443 |
| Source note | uspto-grants-2003_06 |