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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1368912Generated: November 1, 2026

(S)-3-(3-nitrophenyl)-3-phenylacetylaminopropionic acid → (s)-3-Amino-3-(3-nitrophenyl)propionic acid

https://huagongshe.com/reaction/1368912

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-3-(3-nitrophenyl)-3-phenylacetylaminopropionic acidHCID 711905—
SolventHydrochloric AcidHCID 313—
Product(s)-3-Amino-3-(3-nitrophenyl)propionic acidHCID 706689—

Reaction Steps

(S)-3-(3-nitrophenyl)-3-phenylacetylaminopropionic acid is treated with 10 ml of 6N HCl solution. (S)-3-amino-3-(3-nitrophenyl)propionic acid is obtained and is reacted further in analogy to the R enantiomer. This gives (S)-3-{2-[4-(4-methylpyridin-2-ylamino)butyrylamino]acetylamino}-3-(3-nitrophenyl)propionic acid, (S)-3-{2-[4-(4-methylpyridin-2-ylamino)butyrylamino]acetylamino}-3-(3-nitrophenyl propionic acid sodium salt, (S)-3-{2-[4-(4-methylpyridin-2-ylamino)butyrylamino]acetylamino}-3-(3-nitrophenyl)propionic acid trifluoroacetate, RT* 16.89 min, FAB-MS (M+H)+ 444.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06576637B1
Source datasetuspto-grants-2003_06
ORD IDord-cd63b630b65a48349ffa25259de9925d
Source noteuspto-grants-2003_06