2H-Pyran, tetrahydro-2-(2-iodoethoxy)- → 1-{4-[2-(2-Benzyloxyethoxy)ethoxy]phenyl}-2-phenyl-4-(tetrahydropyran-2-yloxy)butan-1-one

Participants

Role	Name	HCID	Charge
Reactant	2H-Pyran, tetrahydro-2-(2-iodoethoxy)-	HCID 11118662	—
Reactant	1-{4-[2-(2-Benzyloxyethoxy)ethoxy]phenyl}-2-phenylethanone	HCID 22504513	—
Product	1-{4-[2-(2-Benzyloxyethoxy)ethoxy]phenyl}-2-phenyl-4-(tetrahydropyran-2-yloxy)butan-1-one	HCID 22504613	—

Reaction Steps

is prepared by using the method described in the example 4d starting from 1-{4-[2-(2-benzyloxyethoxy)ethoxy]phenyl}-2-phenylethanone (8.4g, 21.5 mmol) and 2-(tetrahydropyran-2-yloxy)ethyl iodide (6.6 g, 25.8 mmol). The product (11.7 g) is used in the next reaction step without further purification.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06576645B1
Source dataset	uspto-grants-2003_06
ORD ID	ord-5c73fdff31a3442299357adc639cd053
Source note	uspto-grants-2003_06